Plasma concentrations of sodium salicylate in nursery pigs treated orally

Materials and methods: Stock solutions of liquid ASA and SS products were placed in a nursery environment for 24 hours (Trial One). Salicylate concentrations were measured at 0, 8, 16, and 24 hours using high pressure liquid chromatography (HPLC). In Trial Two, SS was metered into the drinking water of four groups of pigs in a commercial nursery, at stock solution concentrations of 2268 mg per L (T1), 4913 mg per L (T2), 9827 mg per L (T3), and 19,654 mg per L (T4). Controls received nonmedicated water. Plasma salicylate concentrations in 10 pigs per group were measured at 0, 24, 60, and 72 hours.